Bio-Rad AHP1898 PI-3 kinase p110 subunit alpha,Goat anti Human PI-3 kinase p110 subunit alpha antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad AHP1898 PI-3 kinase p110 subunit alpha,Goat anti Human PI-3 kinase p110 subunit alpha antibody

2024-10-22

Goat anti Human PI-3 kinase p110 subunit alpha antibody

货号：AHP1898

规格：0.1 mg

价格：5083

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：PI-3 kinase p110 subunit alpha

物种：人

宿主：山羊

抗体亚型：IgG

荧光染料：Purified

产品介绍
Goat anti Human PI-3 kinase p110 subunit alpha antibodyrecognizes human PI3-kinase p110 subunit alpha (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), otherwise known as PIK3CA, a member of the PI3/PI4-kinase family of lipid kinases, implicated in the regulation of signal transduction during cell growth.PI3-kinase is a heterodimer consisting of a p85 regulatory subunit and a p110 catalytic subunit, which itself is divided into isoforms p110alpha, p110beta, p110delta and p110gamma. Mutations in the PIK3CA gene are associated with breast, ovarian and colorectal cancers (CRC).http://www.omim.org/entry/114500 Colorectal cancer is a heterogeneous disease that is common in both men and women. characterized by malignant lesions arising from the inner wall of the large intestine (the colon) and the rectum (Vehloet al.2005).
产品详情
Target Species	Human
Species Cross-Reactivity	Target Species	Cross Reactivity
Mouse	Expected from Sequence
Rat	Expected from Sequence
Dog	Expected from Sequence
Bovine	Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form	Purified IgG - liquid
Antiserum Preparation	Antiserum to human p110alpha was raised by repeated immunisation of goats with highly purified antigen.Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution	TRIS buffered saline
Preservative Stabilisers	0.02% Sodium Azide (NaN3)0.5% Bovine Serum Albumin
Immunogen	Synthetic peptide C-HQWLKDKNKGEIYD from the internal region of human PI3-kinase p110 subunit alpha (NP_006209.2).
Approx. Protein Concentrations	IgG concentration 0.5 mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Immunohistology - Paraffin¹	√	2.0	3ug/ml
ELISA	√	1/128000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.Histology Positive Control TissueHuman cerebral cortex
数据
Paraffin embedded human brain (cerebellar cortex) stained with Goat anti human p110alpha (AHP1898)。

技术参数

产品应用 E;P

产品类型 Polyclonal Antibody

推荐用于 E;P

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Bio-Rad AHP1898 PI-3 kinase p110 subunit alpha,Goat anti Human PI-3 kinase p110 subunit alpha antibody

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