alpha-1 Antitrypsin Monoclonal Antibody (TMF1#2-1D1)

货号：MIA1102

规格：1 mg

价格：4880

产品类型：流式抗体

品牌：Thermo Fisher

物种：人

宿主：小鼠

抗体亚型：IgG2b

克隆号： TMF1#2-1D1

荧光染料：其它

类型:	单抗	同型对照：
浓度：	2.76 mg/mL	用法：	Assay-Dependent(Flow)

产品详细信息MIA1102 was formerly sold as a Seradyn product.靶标信息Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung. In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma. Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn. Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation. Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.

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