Mouse CD45 ELISA Kit ELISA试剂盒,Mouse CD45 ELISA Kit/小鼠CD45 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse CD45 ELISA Kit ELISA试剂盒,Mouse CD45 ELISA Kit/小鼠CD45 ELISA试剂盒

2024-10-24

Mouse CD45 ELISA Kit/小鼠CD45 ELISA试剂盒

货号：EM14RB,EM14RBX5,EM14RBX10

规格：96 Tests,5X96 Tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：小鼠

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.26 ng/mL
检测范围	0.26-15 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	CD45
Protein aliases	CD45, L-CA, Leukocyte common antigen, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Receptor-type tyrosine-protein phosphatase C, T200
物种（Tested）	小鼠
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	B220, Cd45, CD45R, L-CA, loc, Ly-5, Lyt-4, Ptprc, T200
Gene ID	(Mouse) 19264
Gene symbol	Ptprc
UniProt ID	(Mouse) P06800

Mouse CD45 quantitates mouse CD45 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse CD45.小鼠CD45定量分析血清，血浆，上清液中的小鼠CD45。该检测试剂盒将专门识别天然和重组小鼠CD45。Target information 靶标信息CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling. CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.CD45（LCA，白细胞共同抗原）是在所有有核造血细胞中普遍表达的受体型蛋白质酪氨酸磷酸酶（PTP），约占淋巴细胞所有表面蛋白质的10％。在非造血细胞系，正常和恶性的非造血组织上不存在CD45。 CD45糖蛋白在淋巴细胞发育和抗原信号传导中起着至关重要的作用，是Src家族激酶的重要调节剂。由于选择性剪接，CD45蛋白以多种亚型形式存在，它们的细胞外结构域不同，但共有相同的跨膜结构和胞质结构域。 CD45RA是CD45复合物的同工型，在淋巴样细胞的不同亚型之间表达受到限制。 CD45亚型在转运到富含糖鞘脂的膜结构域中的能力不同，它们的表达取决于细胞类型和细胞的生理状态。已显示CD45是T细胞和B细胞抗原受体信号转导的重要调节剂，并抑制JAK激酶来调节细胞因子受体信号转导。 CD45通过调节整合素介导的信号转导途径，凋亡过程中的DNA片段化以及各种免疫功能的抑制或上调，在促进细胞存活中也很重要。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

技术参数

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://gibcohyclone.cn/thread-47600.htm

特别声明：以上内容(如有图片亦包括在内)来源于授权厂家或网络，如有侵权，请联系删除，本平台不提供信息存储服务。

Notice: The content above (including the pictures if any)comes from authorized manufacturers or networks. In case of infringement, please contact to delete it. This platform does not provide information storage services.

产品询价需求提交

Mouse CD45 ELISA Kit ELISA试剂盒,Mouse CD45 ELISA Kit/小鼠CD45 ELISA试剂盒

相关推荐