p300 Monoclonal Antibody (RW109)/p300单克隆抗体（RW109）

货号：MA1-16623

规格：200 µL

价格：5548

产品类型：抗体和染料

品牌：Thermo Fisher

抗原：Fusion protein containing residues 1572-2371 of hu

物种：其它

宿主：小鼠

抗体亚型：IgG1, kappa

克隆号：RW109

荧光染料：其它

类型:	单抗	同型对照：
浓度：	Conc. Not Determined	用法：	Assay-Dependent(ChIP)；1:100-1:200(ICC)；1:100-1:200(IF)；1:10-1:500(IP)；1:1000(WB)

产品详细信息Suggested positive control: HeLa nuclear extract.靶标信息EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.

数据：

p300 Antibody (MA1-16623) in WBp300 detected in a HeLa nuclear extract using 1 (1:1,000). ECL: 20 minute exposure.

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